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ADVANCING A NEW CLASS OF BIOLOGICS
Pipeline
Advancing a new class of biologics and precision delivery solutions to reduce ischemia reperfusion injury and improve clinical outcomes.
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OUR PIPELINE AT A GLANCE
PROGRAM
INDICATION
APPROACH
STAGE
NEXT MILESTONE
WAV-301
STEMI
Long half-life HGF Mimetic
Preclinical
Human cardiac microtissues and rat MI study
WAV-301 Expansion
ACS / AIC / trauma
IR induced tissue preservation
Discovery/Planning
Indication prioritization
WAV-401
Stroke and CNS ischemia
CNS targeted HGF mimetic
Discovery
BBB-targeted candidate development
Wavefront AI
IR-injury prediction
AI decision support using real world and biomarker data
Concept/Development
Data integration and model design
WHY START WITH STEMI?
PROTECTS THE MICROVASCULATURE
Preserve endothelial integrity and capillary perfusion to reduce no-reflow and microvascular obstruction after reperfusion
CONTROLS PROGRAMMED CELL DEATH
Limits apoptosis and necrosis in stressed but salvageable cells.
REDUCES REMODELING AND FIBROSIS
Mitigates adeverse remodeling and preerves long term organ function.
